BindingDB BDBM50235830 CHEMBL2006765

BDBM50235830 CHEMBL2006765

SMILES CCCNC(=O)c1ccc(Nc2nc(NCC(F)(F)F)c3cc[nH]c3n2)cc1

InChI Key InChIKey=UJBJWYNPUOLFIZ-UHFFFAOYSA-N

Data 65 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50235830

Serine/threonine-protein kinase Sgk1(Homo sapiens (Human))
Abbvie Bioresearch Center

Curated by ChEMBL

BDBM50235830(CHEMBL2006765)

IC50: 606nMAssay Description:Inhibition of SGK1 (unknown origin) after 60 mins by TR-FRET assayMore data for this Ligand-Target Pair

PDB MMDB Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar

CHEMBL PC cid PC sid Similars

Details Article PubMed

Filter my 65 hits

Targets 64▿
- Tyrosine-protein kinase SYK 2
- Serine/threonine-protein kinase D3 1
- Dual specificity tyrosine-phosphorylation-regulated kinase 1B 1
- Death-associated protein kinase 3 1
- Dual specificity tyrosine-phosphorylation-regulated kinase 1A 1
- Cyclin-dependent kinase 9 1
- Cyclin-dependent kinase 8 1
- Cyclin-dependent kinase 7 1
- Serine/threonine-protein kinase pim-1 1
- Serine/threonine-protein kinase TAO2 1
- Mitogen-activated protein kinase kinase kinase kinase 2 1
- Mitogen-activated protein kinase kinase kinase kinase 4 1
- ALK tyrosine kinase receptor 1
- Hepatocyte growth factor receptor 1
- Serine/threonine-protein kinase B-raf 1
- Hepatocyte growth factor-like protein 1
- Glycogen synthase kinase-3 alpha 1
- Leukocyte tyrosine kinase receptor 1
- Glycogen synthase kinase-3 beta 1
- Serine/threonine-protein kinase Nek2 1
- Tyrosine-protein kinase ABL1 1
- Protein kinase C theta type 1
- Dual specificity mitogen-activated protein kinase kinase 2 1
- Serine/threonine-protein kinase PAK 4 1
- Calcium/calmodulin-dependent protein kinase type II subunit alpha 1
- Tyrosine-protein kinase JAK3 1
- Dual specificity mitogen-activated protein kinase kinase 1 1
- Tyrosine-protein kinase JAK2 1
- Proto-oncogene tyrosine-protein kinase receptor Ret 1
- cGMP-dependent protein kinase 1 1
- Rho-associated protein kinase 2 1
- Rho-associated protein kinase 1 1
- Serine/threonine-protein kinase Sgk1 1
- BDNF/NT-3 growth factors receptor 1
- Tyrosine-protein kinase Lck 1
- Dual specificity protein kinase TTK 1
- Tyrosine-protein kinase BTK 1
- NT-3 growth factor receptor 1
- Mitogen-activated protein kinase 9 1
- G protein-coupled receptor kinase 5 1
- Insulin-like growth factor 1 receptor 1
- Dual specificity protein kinase CLK2 1
- High affinity nerve growth factor receptor 1
- Activin receptor type-1 1
- Mitogen-activated protein kinase 8 1
- Inhibitor of nuclear factor kappa-B kinase subunit epsilon 1
- Ribosomal protein S6 kinase alpha-3 1
- Serine/threonine-protein kinase TBK1 1
- Calcium/calmodulin-dependent protein kinase type 1D 1
- Aurora kinase B 1
- Insulin receptor 1
- Vascular endothelial growth factor receptor 2 1
- Fibroblast growth factor receptor 1 1
- Aurora kinase A 1
- Vascular endothelial growth factor receptor 1 1
- Wee1-like protein kinase 1
- Tyrosine-protein kinase receptor TYRO3 1
- Casein kinase I isoform alpha 1
- Tyrosine-protein kinase Fyn 1
- Macrophage colony-stimulating factor 1 receptor 1
- Focal adhesion kinase 1 1
- Platelet-derived growth factor receptor alpha 1
- Activated CDC42 kinase 1 1
- Platelet-derived growth factor receptor beta 1
Publications 1▿
- Bioorg Med Chem Lett 26: 5562-5567 (2016) 65
Institutions 1▿
- Abbvie Bioresearch Center 65
Affinity: 8 to 1.0E+4 nM▿
- IC50 65
- Affinity ≤ nM
Xtal structures: 0
Docked structures: 0
Catalog Cmpds: 0